RNA or CDS feature with sequence discrepancy relative to the assemblyġ.3.3 Features with partial annotation location (e.g. Show on single line with exon structure, no gene barġ.3.2 Features with imperfect match to the assembly 1.3 Special Rendering Styles 1.3.1 Pseudogene features Users can also simplify this track display by filtering the data based on the number of spliced reads. Intron features tracks contain additional track display options, including the ability to sort splice junction features based on the number of spliced reads or by the splice direction (strand). Hover over the feature to see a tooltip that provides additional information, including the end coordinates and intron length. The number of RNA-seq reads supporting the splice junction is reported for each feature. The ends of the features correspond to splice junctions, while the arrow corresponds to the direction of splicing. Intron feature tracks display exon-exon splice junctions based on an analysis of RNA-seq data. Changing these options may result in showing more or fewer features in the track, depending on the underlying source of data in the track. "Show all" "Show parent, Merge children" "Show children, not parent" "Show parent, not children" "Superimpose children on parent". The Feature linking options provide different display views for tracks containing parent and child features i.e. The option "All features on a single line" alway shows the data as a histogram, while the option "All features are expanded" always shows discrete features. By default, most feature tracks are set to "Pack features if necessary", where individual features are shown when zoomed in and the data is displayed as a histogram when zoomed out. Users can set the display resolution using the Rendering Options dropdown menu. The track display settings dialog can be accessed by clicking on the track title, the gear icon on the right side of the track, or by selecting the track within the Tracks configuration menu. in RNA and coding region features) indicate the direction of splicing. White arrows inside features indicate the direction of the feature relative to the top-level sequence. Protein feature or other annotated feature Specialized rendering for SNPs, structural variants, and segmental duplications are described in the later sections of this documentation. These features often derive from files formatted as BED, bigBED, GFF3, GTF, ASN.1, and similar formats. This section describes the rendering used for gene features, RNA and protein models, regulatory sites, and most other feature types. The NCBI Genome Workbench uses similar graphical renderings. On an ending note, CLC Sequence Viewer is a well put-together piece designed to make bioinformatics more approachable, what with its set of features allowing you to explore various scenarios and perform analyses in a user-friendly user interface complemented by a thoroughly documented user manual.This legend applies to NCBI Sequence Viewer. As such, your data input benefits from full integration, not to mention that results can be effortlessly calculated and exported. There is no need to worry about manual data transfers and turn to lots of programs and databases since tCLC Sequence Viewer helps you complete most of the tasks within its GUI. It is also worth pointing out that an impressive number of research tools are integrated, and reports can be generated so that you keep track of molecular weight, composition, and iso electric point. What’s more, reverse complements can be created, and shuffle sequences are supported as well. To be more specific, it can handle multiple alignments of RNA, DNA, and proteins, it is able to determine and manage consensus sequences, and it can also carry out genetic translations. Sports a neat, feature-packed GUIĪs said, the purpose the application serves is to help you try your hand at various basic bioinformatics analyses. Then, a view area allows you to handle one or more tabs at a time, with the side panel enabling you to make adjustments to the tab you are currently working in. What’s more, those who might feel intimidated by the program’s full-featured nature could rest assured that a well-documented user manual is also available for them to browse through in order to make the most of it.įiles are sorted in a navigation area, and just below, a toolbox is included. The first thing that stands out when opening CLC Sequence Viewer is the impressive number of features packed in the GUI, which still manages to feel uncluttered and user-friendly. Helps you perform bioinformatics analyses ![]() The program provides you with all-encompassing functionality so that you can also manage data, view graphics, and choose from a multitude of options when it comes to output formats. If bioinformatics is your field, and you require a powerful software solution to help you carry out thorough analyses, CLC Sequence Viewer might be up to the task.
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